human MTNR1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MTNR1B.
shAAV-216034
AAV-h-MTNR1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MTNR1B (melatonin receptor 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FGQTL2; MEL-1B-R; MT2
Description (Vector)
MTNR1B encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. MTNR1B product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Gene ID
4544
Gene Name (Vector)
melatonin receptor 1B
Gene Symbol
MTNR1B
HGNC ID
HGNC:7464
ORF Size (aa)
1089
ORF Size (bp)
1089 bp
RefSeq ID
NM_005959
RefSeq Synonyms
NM_005959, BC069163,
Species
human
UniGene ID
Hs.569039
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.