human DHFR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DHFR.
shAAV-215906
AAV-h-DHFR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DHFR (dihydrofolate reductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHFRP1; DYR
Description (Vector)
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
Gene ID
1719
Gene Name (Vector)
dihydrofolate reductase
Gene Symbol
DHFR
HGNC ID
HGNC:2861
ORF Size (aa)
564
ORF Size (bp)
564 bp
RefSeq ID
NM_000791
RefSeq Synonyms
NM_001290357, NM_001290354, NM_000791, BC071996, BC070280, BC003584, BC000192,
Species
human
UniGene ID
Hs.648635
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.