human EDF1 Over-expression AAV

Name 
AAV-h-EDF1
Cat No 
AAV-207562
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EDF1.

AAV-207562
AAV-h-EDF1

Ready-to-use AAV expressing Human EDF1 (endothelial differentiation related factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CFAP280; EDF-1; endothelial differentiation-related factor 1; MBF1; multiprotein bridging factor 1; Multiprotein-bridging factor 1
Description (eCommerce)
Endothelial differentiation-related factor 1 (EDF-1) is a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. EDF-1 has also been found to act as a transcriptional co-activator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators [taken from NCBI Entrez Gene (Gene ID: 8721)].
Description (Vector)
EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.
Gene ID
8721
Gene Name (eCommerce)
endothelial differentiation related factor 1
Gene Name (Vector)
endothelial differentiation related factor 1
Gene Symbol
EDF1
HGNC ID
HGNC:3164
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
447
Protein Name (eCommerce)
Endothelial differentiation-related factor 1
RefSeq ID
NM_003792
RefSeq Synonyms
NM_153200, NM_003792, NM_001281299, NM_001281298, NM_001281297, BC015500,
Research Areas
Metabolism/Metabolic Process,Methyltransferase,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Endothelial differentiation-related factor 1 (EDF-1) is a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. EDF-1 has also been found to act as a transcriptional co-activator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators [taken from NCBI Entrez Gene (Gene ID: 8721)].
UniGene ID
Hs.174050
UniProt ID (eCommerce)
O60869

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.