human MRC2 shRNA silencing AAV

Name 
AAV-h-MRC2-shRNA
Cat No 
shAAV-215748
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MRC2.

shAAV-215748
AAV-h-MRC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MRC2 (mannose receptor C type 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD280; CLEC13E; ENDO180; UPARAP
Description (Vector)
MRC2 encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
Gene ID
9902
Gene Name (Vector)
mannose receptor C type 2
Gene Symbol
MRC2
HGNC ID
HGNC:16875
ORF Size (aa)
4440
ORF Size (bp)
4440 bp
RefSeq ID
NM_006039
RefSeq Synonyms
NM_006039, BC153884, BC150212, BC146647,
Species
human
UniGene ID
Hs.7835

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.