human MOG shRNA silencing AAV

Name 
AAV-h-MOG-shRNA
Cat No 
shAAV-215632
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MOG.

shAAV-215632
AAV-h-MOG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MOG (myelin oligodendrocyte glycoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BTN6; BTNL11; MOGIG2; NRCLP7
Description (Vector)
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
4340
Gene Name (Vector)
myelin oligodendrocyte glycoprotein
Gene Symbol
MOG
HGNC ID
HGNC:7197
ORF Size (aa)
888
RefSeq ID
NM_002433
RefSeq Synonyms
NM_206814, NM_206812, NM_206811, NM_206810, NM_206809, NM_002433, NM_001170418, NM_001008229, NM_001008228, BC035938,
Species
human
UniGene ID
Hs.141308

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.