human MLYCD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MLYCD.
shAAV-215545
AAV-h-MLYCD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MLYCD (malonyl-CoA decarboxylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCD
Description (Vector)
The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.
Gene ID
23417
Gene Name (Vector)
malonyl-CoA decarboxylase
Gene Symbol
MLYCD
HGNC ID
HGNC:7150
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_012213
RefSeq Synonyms
NM_012213, BC052592, BC000286,
Species
human
UniGene ID
Hs.644610
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.