human MLXIPL shRNA silencing AAV

Name 
AAV-h-MLXIPL-shRNA
Cat No 
shAAV-215543
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MLXIPL.

shAAV-215543
AAV-h-MLXIPL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MLXIPL (MLX interacting protein like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHd14; CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH
Description (Vector)
MLXIPL encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
Gene ID
51085
Gene Name (Vector)
MLX interacting protein like
Gene Symbol
MLXIPL
HGNC ID
HGNC:12744
ORF Size (aa)
2166
ORF Size (bp)
2166 bp
RefSeq ID
NM_032951
RefSeq Synonyms
NM_032954, NM_032953, NM_032952, NM_032951, BC012925,
Species
human
UniGene ID
Hs.647055

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.