human MLC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MLC1.
shAAV-215510
AAV-h-MLC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MLC1 (megalencephalic leukoencephalopathy with subcortical cysts 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LVM; MLC; VL
Description (Vector)
The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
23209
Gene Name (Vector)
megalencephalic leukoencephalopathy with subcortical cysts 1
Gene Symbol
MLC1
HGNC ID
HGNC:17082
ORF Size (aa)
1134
RefSeq ID
NM_015166
RefSeq Synonyms
NM_139202, NM_015166, BC070042, BC028425, BC010518,
Species
human
UniGene ID
Hs.517729
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.