human MKS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MKS1.
shAAV-215507
AAV-h-MKS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MKS1 (Meckel syndrome, type 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BBS13; JBTS28; MES; MKS; POC12
Description (Vector)
MKS1 localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
54903
Gene Name (Vector)
Meckel syndrome, type 1
Gene Symbol
MKS1
HGNC ID
HGNC:7121
ORF Size (aa)
1134
ORF Size (bp)
1134 bp
RefSeq ID
NM_017777
RefSeq Synonyms
NM_017777, NM_001330397, NM_001321269, NM_001321268, NM_001165927, BC010061,
Species
human
UniGene ID
Hs.408843
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.