human MKRN2 shRNA silencing AAV

Name
AAV-h-MKRN2-shRNA

Cat No
shAAV-215505

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MKRN2.

shAAV-215505

AAV-h-MKRN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MKRN2 (makorin ring finger protein 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HSPC070; makorin RING zinc-finger protein 2; probable E3 ubiquitin-protein ligase makorin-2; RING finger protein 62; RING-type E3 ubiquitin transferase makorin-2; RNF62

Description (eCommerce)

MKRN2 is a RING zinc finger protein whose function has not yet been determined.

Description (Vector)

Members of the makorin family, including MKRN2, have a characteristic zinc finger composition that suggests that they are ribonucleoproteins (Gray et al., 2001 (PubMed 11597136)).(supplied by OMIM, Mar 2008)

Gene ID

23609

Gene Name (eCommerce)

makorin ring finger protein 2

Gene Name (Vector)

makorin ring finger protein 2

Gene Symbol

MKRN2

HGNC ID

HGNC:7113

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1251

ORF Size (bp)

1251 bp

Protein Name (eCommerce)

Probable E3 ubiquitin-protein ligase makorin-2

RefSeq ID

NM_014160

RefSeq Synonyms

NM_014160, NM_001271707, BC015715,

Research Areas

Cancer,Prostate Cancer,Ubiquitination,Zinc-finger

Research Areas (Faceted)

cancer,cell_biology

Species

human

Target Sentence

MKRN2 is a RING zinc finger protein whose function has not yet been determined.

UniGene ID

Hs.591666

UniProt ID (eCommerce)

Q9H000

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.