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human MKKS shRNA silencing AAV

Name 
AAV-h-MKKS-shRNA
Cat No 
shAAV-215496
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MKKS.

shAAV-215496
AAV-h-MKKS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MKKS (McKusick-Kaufman syndrome). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BBS6; HMCS; KMS; MKS
Description (Vector)
MKKS encodes a protein which shares sequence similarity with other members of the chaperonin family. The encoded protein may have a role in protein folding, processing and assembly. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6 and McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
8195
Gene Name (Vector)
McKusick-Kaufman syndrome
Gene Symbol
MKKS
HGNC ID
HGNC:7108
ORF Size (aa)
1713
ORF Size (bp)
1713 bp
RefSeq ID
NM_170784
RefSeq Synonyms
NM_170784, NM_018848, BC028973,
Species
human
UniGene ID
Hs.472119

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.