human MIS12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MIS12.
shAAV-215487
AAV-h-MIS12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MIS12 (MIS12, kinetochore complex component). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2510025F08Rik; hMis12; homolog of yeast Mis12; KNTC2AP; MIS12 homolog; MIS12, MIND kinetochore complex component, homolog; MTW1; protein MIS12 homolog
Description (eCommerce)
MIS12 is an inner kinetochore protein found in a complex with Dsn1, Nnf1, and Nsl1 that functions in kinetochore assembly. This MIS12 complex has been demonstrated to be required for proper chromosome alignment and cell cycle progression.
Gene ID
79003
Gene Name (eCommerce)
MIS12, kinetochore complex component
Gene Name (Vector)
MIS12, kinetochore complex component
Gene Symbol
MIS12
HGNC ID
HGNC:24967
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
618
ORF Size (bp)
618 bp
Protein Name (eCommerce)
Protein MIS12 homolog
RefSeq ID
NM_024039
RefSeq Synonyms
NM_024039, NM_001258220, NM_001258219, NM_001258218, NM_001258217, BC000229,
Research Areas
Cell Cycle,Cell Division
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
MIS12 is an inner kinetochore protein found in a complex with Dsn1, Nnf1, and Nsl1 that functions in kinetochore assembly. This MIS12 complex has been demonstrated to be required for proper chromosome alignment and cell cycle progression.
UniGene ID
Hs.267194
UniProt ID (eCommerce)
Q9H081
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.