human MIER1 shRNA silencing AAV

Name 
AAV-h-MIER1-shRNA
Cat No 
shAAV-215461
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MIER1.

shAAV-215461
AAV-h-MIER1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MIER1 (MIER1 transcriptional regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ER1; MI-ER1
Description (Vector)
MIER1 encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). In human, this gene functions as a growth-factor-induced immediate early gene that encodes a transcriptional regulator. Depending on the cellular context, this gene can function as both an activator and repressor of gene transcription. Alternative splicing results in multiple isoforms; some of which contain a nuclear localization signal.
Gene ID
57708
Gene Name (Vector)
MIER1 transcriptional regulator
Gene Symbol
MIER1
HGNC ID
HGNC:29657
ORF Size (aa)
1113
ORF Size (bp)
1113 bp
RefSeq ID
NM_020948
RefSeq Synonyms
NM_020948, NM_001278215, NM_001146113, NM_001146112, NM_001146111, NM_001146110, NM_001077704, NM_001077703, NM_001077702, NM_001077701, NM_001077700, BC125218, BC125217, BC108726,
Species
human
UniGene ID
Hs.652983

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.