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human MGST3 shRNA silencing AAV

Name 
AAV-h-MGST3-shRNA
Cat No 
shAAV-215433
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MGST3.

shAAV-215433
AAV-h-MGST3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MGST3 (microsomal glutathione S-transferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GST-III
Description (Vector)
MGST3 encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. MGST3 encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.
Gene ID
4259
Gene Name (Vector)
microsomal glutathione S-transferase 3
Gene Symbol
MGST3
HGNC ID
HGNC:7064
ORF Size (aa)
459
RefSeq ID
NM_004528
RefSeq Synonyms
NM_004528, BC005964, BC003034, BC000505,
Species
human
UniGene ID
Hs.191734

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.