human MGA shRNA silencing AAV

Name 
AAV-h-MGA-shRNA
Cat No 
shAAV-215388
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MGA.

shAAV-215388
AAV-h-MGA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MGA (MGA, MAX dimerization protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MAD5; MAX dimerization protein 5; MAX gene-associated protein; MXD5
Description (eCommerce)
MGA (MAX gene-associated protein) functions as a dual-specificity transcription factor which regulates the expression of both MAX-network and T-box family target genes. MGA function is activated by heterodimerization with MAX. MGA can function as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IWI9].
Gene ID
23269
Gene Name (eCommerce)
MGA, MAX dimerization protein
Gene Name (Vector)
MGA, MAX dimerization protein
Gene Symbol
MGA
HGNC ID
HGNC:14010
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
8571
ORF Size (bp)
8571 bp
Protein Name (eCommerce)
MAX gene-associated protein
RefSeq ID
NM_001080541
RefSeq Synonyms
NM_001164273, NM_001080541, BC136659,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
MGA (MAX gene-associated protein) functions as a dual-specificity transcription factor which regulates the expression of both MAX-network and T-box family target genes. MGA function is activated by heterodimerization with MAX. MGA can function as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IWI9].
UniGene ID
Hs.187569
UniProt ID (eCommerce)
Q8IWI9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.