human MFSD8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MFSD8.
shAAV-215386
AAV-h-MFSD8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MFSD8 (major facilitator superfamily domain containing 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCMD; CLN7
Description (Vector)
MFSD8 encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL).
Gene ID
256471
Gene Name (Vector)
major facilitator superfamily domain containing 8
Gene Symbol
MFSD8
HGNC ID
HGNC:28486
ORF Size (aa)
1557
ORF Size (bp)
1557 bp
RefSeq ID
NM_152778
RefSeq Synonyms
NM_152778, BC029503,
Species
human
UniGene ID
Hs.480701
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.