human MFNG shRNA silencing AAV

Name 
AAV-h-MFNG-shRNA
Cat No 
shAAV-215369
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MFNG.

shAAV-215369
AAV-h-MFNG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MFNG (MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
MFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
Gene ID
4242
Gene Name (Vector)
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Gene Symbol
MFNG
HGNC ID
HGNC:7038
ORF Size (aa)
966
ORF Size (bp)
966 bp
RefSeq ID
NM_002405
RefSeq Synonyms
NM_002405, NM_001166343, BC094814,
Species
human
UniGene ID
Hs.517603

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.