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human MEPCE shRNA silencing AAV

Name 
AAV-h-MEPCE-shRNA
Cat No 
shAAV-215305
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MEPCE.

shAAV-215305
AAV-h-MEPCE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MEPCE (methylphosphate capping enzyme). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
7SK snRNA methylphosphate capping enzyme; BCDIN3; bicoid-interacting protein 3 homolog; bin3 homolog; bin3, bicoid-interacting 3, homolog; MePCE
Description (eCommerce)
7SK snRNA methylphosphate capping enzyme (MEPC) is an S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7L2J0].
Gene ID
56257
Gene Name (eCommerce)
methylphosphate capping enzyme
Gene Name (Vector)
methylphosphate capping enzyme
Gene Symbol
MEPCE
HGNC ID
HGNC:20247
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2070
ORF Size (bp)
2070 bp
Protein Name (eCommerce)
7SK snRNA methylphosphate capping enzyme
RefSeq ID
NM_019606
RefSeq Synonyms
NM_019606, NM_001194992, NM_001194991, NM_001194990, BC018935, BC016396, BC000556,
Research Areas
Methyltransferase,RNA Processing,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
7SK snRNA methylphosphate capping enzyme (MEPC) is an S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7L2J0].
UniGene ID
Hs.178011
UniProt ID (eCommerce)
Q7L2J0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.