human ME2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ME2.
shAAV-215226
AAV-h-ME2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ME2 (malic enzyme 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ODS1
Description (Vector)
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
Gene ID
4200
Gene Name (Vector)
malic enzyme 2
Gene Symbol
ME2
HGNC ID
HGNC:6984
ORF Size (aa)
1440
ORF Size (bp)
1440 bp
RefSeq ID
NM_002396
RefSeq Synonyms
NM_002396, NM_001168335, BC000147,
Species
human
UniGene ID
Hs.233119
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.