human MDH1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MDH1.
shAAV-215214
AAV-h-MDH1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MDH1 (malate dehydrogenase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEL-S-32; MDH-s; MDHA; MGC:1375; MOR2
Description (Vector)
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
4190
Gene Name (Vector)
malate dehydrogenase 1
Gene Symbol
MDH1
HGNC ID
HGNC:6970
ORF Size (aa)
1005
ORF Size (bp)
1005 bp
RefSeq ID
NM_005917
RefSeq Synonyms
NM_005917, NM_001316374, NM_001199112, NM_001199111, BC001484,
Species
human
UniGene ID
Hs.526521
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.