human MCC shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MCC.
shAAV-215155
AAV-h-MCC-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MCC (mutated in colorectal cancers). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCC1
Description (Vector)
MCC is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4163
Gene Name (Vector)
mutated in colorectal cancers
Gene Symbol
MCC
HGNC ID
HGNC:6935
ORF Size (aa)
2490
ORF Size (bp)
2490 bp
RefSeq ID
NM_002387
RefSeq Synonyms
NM_002387, NM_001085377, BC018919, BC009279,
Species
human
UniGene ID
Hs.593171
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.