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human MC4R shRNA silencing AAV

Name 
AAV-h-MC4R-shRNA
Cat No 
shAAV-215141
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MC4R.

shAAV-215141
AAV-h-MC4R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MC4R (melanocortin 4 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
MC4R is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
Gene ID
4160
Gene Name (Vector)
melanocortin 4 receptor
Gene Symbol
MC4R
HGNC ID
HGNC:6932
ORF Size (aa)
999
ORF Size (bp)
999 bp
RefSeq ID
NM_005912
RefSeq Synonyms
NM_005912, BC111992, BC101802, BC069172,
Species
human
UniGene ID
Hs.532833

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.