human MB shRNA silencing AAV

Name
AAV-h-MB-shRNA

Cat No
shAAV-215086

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MB.

shAAV-215086

AAV-h-MB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MB (myoglobin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

myoglobgin;myoglobin;PVALB

Description (eCommerce)

Myoglobin is a protein responsible for binding both oxygen and iron, and is typically localized to heart and skeletal muscle tissue in mammals.

Description (Vector)

MB encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported.

Gene ID

4151

Gene Name (eCommerce)

myoglobin

Gene Name (Vector)

myoglobin

Gene Symbol

HGNC ID

HGNC:6915

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

300

Protein Name (eCommerce)

Myoglobin

RefSeq ID

NM_203377

RefSeq Synonyms

NM_203378, NM_203377, NM_005368, BC018001, BC014547,

Research Areas

Cardiac Development,Cardiology,Cardiovascular,Hypoxia

Research Areas (Faceted)

cardiovascular,cell_biology,developmental_biology

Species

human

Target Sentence

Myoglobin is a protein responsible for binding both oxygen and iron, and is typically localized to heart and skeletal muscle tissue in mammals.

UniGene ID

Hs.517586

UniProt ID (eCommerce)

P02144

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.