human MAT1A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MAT1A.
shAAV-215062
AAV-h-MAT1A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MAT1A (methionine adenosyltransferase 1A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MAT; MATA1; SAMS; SAMS1
Description (Vector)
MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
Gene ID
4143
Gene Name (Vector)
methionine adenosyltransferase 1A
Gene Symbol
MAT1A
HGNC ID
HGNC:6903
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_000429
RefSeq Synonyms
NM_000429, BC018359,
Species
human
UniGene ID
Hs.282670
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.