human MASP2 shRNA silencing AAV

Name 
AAV-h-MASP2-shRNA
Cat No 
shAAV-215059
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MASP2.

shAAV-215059
AAV-h-MASP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MASP2 (mannan binding lectin serine peptidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MAP19; MASP-2; MASP1P1; sMAP
Description (Vector)
The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin pathway of complement activation. The longer isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases.
Gene ID
10747
Gene Name (Vector)
mannan binding lectin serine peptidase 2
Gene Symbol
MASP2
HGNC ID
HGNC:6902
ORF Size (aa)
2058
ORF Size (bp)
2058 bp
RefSeq ID
NM_006610
RefSeq Synonyms
NM_139208, NM_006610, BC156886, BC156086,
Species
human
UniGene ID
Hs.655645

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.