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human MAPK8IP3 shRNA silencing AAV

Name 
AAV-h-MAPK8IP3-shRNA
Cat No 
shAAV-214991
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAPK8IP3.

shAAV-214991
AAV-h-MAPK8IP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
JIP-3; JIP3; JSAP1; syd; SYD2
Description (Vector)
MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
23162
Gene Name (Vector)
mitogen-activated protein kinase 8 interacting protein 3
Gene Symbol
MAPK8IP3
HGNC ID
HGNC:6884
ORF Size (aa)
4014
ORF Size (bp)
4014 bp
RefSeq ID
NM_015133
RefSeq Synonyms
NM_015133, NM_001318852, NM_001040439, BC150266, BC144486, BC137124, BC137123,
Species
human
UniGene ID
Hs.207763

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.