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human MAP3K10 shRNA silencing AAV

Name 
AAV-h-MAP3K10-shRNA
Cat No 
shAAV-214923
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAP3K10.

shAAV-214923
AAV-h-MAP3K10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP3K10 (mitogen-activated protein kinase kinase kinase 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MEKK10; MLK2; MST
Description (Vector)
MAP3K10 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Gene ID
4294
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 10
Gene Symbol
MAP3K10
HGNC ID
HGNC:6849
ORF Size (aa)
2862
ORF Size (bp)
2862 bp
RefSeq ID
NM_002446
RefSeq Synonyms
NM_002446, BC111460,
Species
human
UniGene ID
Hs.466743

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.