human MAP1S shRNA silencing AAV

Name
AAV-h-MAP1S-shRNA

Cat No
shAAV-214909

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MAP1S.

shAAV-214909

AAV-h-MAP1S-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP1S (microtubule associated protein 1S). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BPY2-interacting protein 1; BPY2IP1; C19orf5; MAP-1S; MAP8; microtubule-associated protein 1S; microtubule-associated protein 8; variable charge Y chromosome 2-interacting protein 1; VCY2-interacting protein 1; VCY2IP1; VCY2IP-1

Description (eCommerce)

Microtubule-associated protein 1S (MAP1S) is a microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). MAP1S plays a role in anchoring the microtubule-organizing center to the centrosomes. MAP1S also binds to DNA, plays a role in apoptosis, and is involved in the formation of microtubule bundles [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q66K74].

Gene ID

55201

Gene Name (eCommerce)

microtubule associated protein 1S

Gene Name (Vector)

microtubule associated protein 1S

Gene Symbol

MAP1S

HGNC ID

HGNC:15715

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3180

ORF Size (bp)

3180 bp

Protein Name (eCommerce)

Microtubule-associated protein 1S

RefSeq ID

NM_018174

RefSeq Synonyms

NM_018174, NM_001308363, BC113952, BC080547,

Research Areas

Apoptosis,Brain Development,Cell Cycle,Cytoskeleton,Neurobiology,Neurodevelopment,Synapse

Research Areas (Faceted)

cell_biology,cell_cycle,developmental_biology,genetics,neurobiology

Species

human

Target Sentence

Microtubule-associated protein 1S (MAP1S) is a microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). MAP1S plays a role in anchoring the microtubule-organizing center to the centrosomes. MAP1S also binds to DNA, plays a role in apoptosis, and is involved in the formation of microtubule bundles [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q66K74].

UniGene ID

Hs.66048

UniProt ID (eCommerce)

Q66K74

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.