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human MAP1LC3A shRNA silencing AAV

Name 
AAV-h-MAP1LC3A-shRNA
Cat No 
shAAV-214900
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAP1LC3A.

shAAV-214900
AAV-h-MAP1LC3A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
89
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3
Description (Vector)
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Gene ID
84557
Gene Name (Vector)
microtubule associated protein 1 light chain 3 alpha
Gene Symbol
MAP1LC3A
HGNC ID
HGNC:6838
ORF Size (aa)
366
RefSeq ID
NM_032514
RefSeq Synonyms
NM_181509, NM_032514, BC015810,
Species
human
UniGene ID
Hs.632273

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.