human MAK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MAK.
shAAV-214853
AAV-h-MAK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MAK (male germ cell associated kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RP62
Description (Vector)
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
4117
Gene Name (Vector)
male germ cell associated kinase
Gene Symbol
MAK
HGNC ID
HGNC:6816
ORF Size (aa)
1374
ORF Size (bp)
1374 bp
RefSeq ID
NM_005906
RefSeq Synonyms
NM_005906, NM_001242957, NM_001242385, BC039825,
Species
human
UniGene ID
Hs.446125
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.