human LY96 shRNA silencing AAV

Name 
AAV-h-LY96-shRNA
Cat No 
shAAV-214704
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LY96.

shAAV-214704
AAV-h-LY96-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LY96 (lymphocyte antigen 96). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ESOP-1; ly-96; MD-2; MD2
Description (Vector)
LY96 encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
23643
Gene Name (Vector)
lymphocyte antigen 96
Gene Symbol
LY96
HGNC ID
HGNC:17156
ORF Size (aa)
483
RefSeq ID
NM_015364
RefSeq Synonyms
NM_015364, NM_001195797, BC020690,
Species
human
UniGene ID
Hs.660766

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.