human LRRC8E shRNA silencing AAV

Name
AAV-h-LRRC8E-shRNA

Cat No
shAAV-214597

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LRRC8E.

shAAV-214597

AAV-h-LRRC8E-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LRRC8E (leucine rich repeat containing 8 family member E). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

LRRC8E encodes a member of a small, conserved family of proteins with similar structure, including a string of extracellular leucine-rich repeats. A related protein was shown to be involved in B-cell development. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

80131

Gene Name (Vector)

leucine rich repeat containing 8 family member E

Gene Symbol

LRRC8E

HGNC ID

HGNC:26272

ORF Size (aa)

2391

ORF Size (bp)

2391 bp

RefSeq ID

NM_025061

RefSeq Synonyms

NM_025061, NM_001268285, NM_001268284, BC070089, BC022216,

Species

human

UniGene ID

Hs.501511

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.