human LRIG1 shRNA silencing AAV

Name
AAV-h-LRIG1-shRNA

Cat No
shAAV-214484

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human LRIG1.

shAAV-214484

AAV-h-LRIG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LRIG1 (leucine rich repeats and immunoglobulin like domains 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin-like domains protein 1; LIG1; LIG-1; ortholog of mouse integral membrane glycoprotein LIG-1

Description (eCommerce)

LRIG1 is a transmembrane protein that contains a large number of leucine-rich repeats that localizes to the surface of cells and antagonizes ERBB receptor signaling (Wang et al, 2013)

Gene ID

26018

Gene Name (eCommerce)

leucine rich repeats and immunoglobulin like domains 1

Gene Name (Vector)

leucine rich repeats and immunoglobulin like domains 1

Gene Symbol

LRIG1

HGNC ID

HGNC:17360

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3282

ORF Size (bp)

3282 bp

Protein Name (eCommerce)

Leucine-rich repeats and immunoglobulin-like domains protein 1

RefSeq ID

NM_015541

RefSeq Synonyms

NM_015541, BC140907, BC071561,

Research Areas

Cancer,EGFR Signaling,EGFR Signaling in Cancer,Immunology,Signal Transduction

Research Areas (Faceted)

cancer,signal_transduction,cancer,immunology

Species

human

Target Sentence

LRIG1 is a transmembrane protein that contains a large number of leucine-rich repeats that localizes to the surface of cells and antagonizes ERBB receptor signaling (Wang et al, 2013)

UniGene ID

Hs.518055

UniProt ID (eCommerce)

Q96JA1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.