human PDE5A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDE5A.
shAAV-214408
AAV-h-PDE5A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDE5A (phosphodiesterase 5A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGB-PDE; CN5A; PDE5
Description (Vector)
PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Gene ID
8654
Gene Name (Vector)
phosphodiesterase 5A
Gene Symbol
PDE5A
HGNC ID
HGNC:8784
ORF Size (aa)
2628
ORF Size (bp)
2628 bp
RefSeq ID
NM_001083
RefSeq Synonyms
NM_033437, NM_033430, NM_001083, BC126233,
Species
human
UniGene ID
Hs.587281
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.