human OSBPL5 shRNA silencing AAV

Name 
AAV-h-OSBPL5-shRNA
Cat No 
shAAV-214185
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OSBPL5.

shAAV-214185
AAV-h-OSBPL5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OSBPL5 (oxysterol binding protein like 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OBPH1; ORP5
Description (Vector)
OSBPL5 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. OSBPL5 has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.
Gene ID
114879
Gene Name (Vector)
oxysterol binding protein like 5
Gene Symbol
OSBPL5
HGNC ID
HGNC:16392
ORF Size (aa)
2436
ORF Size (bp)
2436 bp
RefSeq ID
NM_020896
RefSeq Synonyms
NM_145638, NM_020896, NM_001144063, BC039579, BC032646,
Species
human
UniGene ID
Hs.436166

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.