human H3F3A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human H3F3A.
shAAV-214180
AAV-h-H3F3A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human H3F3A (H3 histone family member 3A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H3.3A; H3F3
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.
Gene ID
3020
Gene Name (Vector)
H3 histone family member 3A
Gene Symbol
H3F3A
HGNC ID
HGNC:4764
ORF Size (aa)
411
RefSeq ID
NM_002107
RefSeq Synonyms
NM_002107, BC095447, BC081561, BC038989, BC029405,
Species
human
UniGene ID
Hs.533624
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.