human LMX1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LMX1B.
shAAV-214052
AAV-h-LMX1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LMX1B (LIM homeobox transcription factor 1 beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LMX1.2; NPS1
Description (Vector)
LMX1B encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
4010
Gene Name (Vector)
LIM homeobox transcription factor 1 beta
Gene Symbol
LMX1B
HGNC ID
HGNC:6654
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_002316
RefSeq Synonyms
NM_002316, NM_001174147, NM_001174146, BC143801, BC113491, BC112120, BC069601,
Species
human
UniGene ID
Hs.129133
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.