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human LILRA5 shRNA silencing AAV

Name 
AAV-h-LILRA5-shRNA
Cat No 
shAAV-213932
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LILRA5.

shAAV-213932
AAV-h-LILRA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LILRA5 (leukocyte immunoglobulin like receptor A5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD85; CD85F; ILT-11; ILT11; LILRB7; LIR-9; LIR9
Description (Vector)
LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
353514
Gene Name (Vector)
leukocyte immunoglobulin like receptor A5
Gene Symbol
LILRA5
HGNC ID
HGNC:16309
ORF Size (aa)
762
RefSeq ID
NM_021250
RefSeq Synonyms
NM_181986, NM_181985, NM_181879, NM_021250, BC153203, BC148658,
Species
human
UniGene ID
Hs.710986

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.