human LCMT2 shRNA silencing AAV

Name
AAV-h-LCMT2-shRNA

Cat No
shAAV-213754

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LCMT2.

shAAV-213754

AAV-h-LCMT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LCMT2 (leucine carboxyl methyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PPM2; TYW4

Description (Vector)

The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).

Gene ID

9836

Gene Name (Vector)

leucine carboxyl methyltransferase 2

Gene Symbol

LCMT2

HGNC ID

HGNC:17558

ORF Size (aa)

2061

ORF Size (bp)

2061 bp

RefSeq ID

NM_014793

RefSeq Synonyms

NM_014793, BC015949,

Species

human

UniGene ID

Hs.200596

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.