human LBR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LBR.
shAAV-213715
AAV-h-LBR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LBR (lamin B receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHCR14B; LMN2R; PHA; TDRD18
Description (Vector)
LBR belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Gene ID
3930
Gene Name (Vector)
lamin B receptor
Gene Symbol
LBR
HGNC ID
HGNC:6518
ORF Size (aa)
1848
ORF Size (bp)
1848 bp
RefSeq ID
NM_002296
RefSeq Synonyms
NM_194442, NM_002296, BC020079,
Species
human
UniGene ID
Hs.435166
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.