human LBP shRNA silencing AAV

Name
AAV-h-LBP-shRNA

Cat No
shAAV-213714

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LBP.

shAAV-213714

AAV-h-LBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LBP (lipopolysaccharide binding protein). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BPIFD2

Description (Vector)

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

Gene ID

3929

Gene Name (Vector)

lipopolysaccharide binding protein

Gene Symbol

LBP

HGNC ID

HGNC:6517

ORF Size (aa)

1434

ORF Size (bp)

1434 bp

RefSeq ID

NM_004139

RefSeq Synonyms

NM_004139, BC022256,

Species

human

UniGene ID

Hs.154078

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.