human LAT2 shRNA silencing AAV

Name
AAV-h-LAT2-shRNA

Cat No
shAAV-213703

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LAT2.

shAAV-213703

AAV-h-LAT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LAT2 (linker for activation of T-cells family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HSPC046; LAB; NTAL; WBSCR15; WBSCR5; WSCR5

Description (Vector)

LAT2 is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. LAT2 consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.

Gene ID

7462

Gene Name (Vector)

linker for activation of T-cells family member 2

Gene Symbol

LAT2

HGNC ID

HGNC:12749

ORF Size (aa)

732

RefSeq ID

NM_014146

RefSeq Synonyms

NM_032464, NM_032463, NM_014146, BC009204, BC001609,

Species

human

UniGene ID

Hs.647049

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.