human LASS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CERS2.
shAAV-213693
AAV-h-LASS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CERS2 (ceramide synthase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ceramide synthase 2; CerS2; L3; LAG1 homolog, ceramide synthase 2; LAG1 longevity assurance 2; LAG1 longevity assurance homolog 2; LASS2; longevity assurance (LAG1, S. cerevisiae) homolog 2; SP260; TMSG1; tumor metastasis-suppressor gene 1 protein
Description (eCommerce)
Human ceramide synthase 2 has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth [taken from NCBI Entrez Gene (Gene ID: 29956)].
Description (Vector)
CERS2 encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
Gene ID
29956
Gene Name (eCommerce)
ceramide synthase 2
Gene Name (Vector)
ceramide synthase 2
Gene Symbol
CERS2
HGNC ID
HGNC:14076
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1143
ORF Size (bp)
1143 bp
Protein Name (eCommerce)
Ceramide synthase 2
RefSeq ID
NM_022075
RefSeq Synonyms
NM_181746, NM_022075, BC010032, BC001357,
Research Areas
Metabolism/Metabolic Process,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Human ceramide synthase 2 has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth [taken from NCBI Entrez Gene (Gene ID: 29956)].
UniGene ID
Hs.713103
UniProt ID (eCommerce)
Q96G23
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.