human LAMA2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LAMA2.
shAAV-213646
AAV-h-LAMA2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LAMA2 (laminin subunit alpha 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LAMM
Description (Vector)
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.
Gene ID
3908
Gene Name (Vector)
laminin subunit alpha 2
Gene Symbol
LAMA2
HGNC ID
HGNC:6482
ORF Size (aa)
9369
ORF Size (bp)
9369 bp
RefSeq ID
NM_000426
RefSeq Synonyms
NM_001079823, NM_000426, BC172564, BC172257,
Species
human
UniGene ID
Hs.200841
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.