human LACTB shRNA silencing AAV

Name 
AAV-h-LACTB-shRNA
Cat No 
shAAV-213632
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LACTB.

shAAV-213632
AAV-h-LACTB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LACTB (lactamase beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
G24; MRPL56
Description (Vector)
LACTB encodes a protein from the large 39S subunit of the mitochondrial ribosome (mitoribosome). The encoded protein has some sequence similarity to prokaryotic beta-lactamases but most of the residues that are responsible for the beta-lactamase activity are not conserved between the two proteins. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Gene ID
114294
Gene Name (Vector)
lactamase beta
Gene Symbol
LACTB
HGNC ID
HGNC:16468
ORF Size (aa)
1644
ORF Size (bp)
1644 bp
RefSeq ID
NM_032857
RefSeq Synonyms
NM_171846, NM_032857, NM_001288585, BC067288,
Species
human
UniGene ID
Hs.410388

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.