human LACRT shRNA silencing AAV

Name 
AAV-h-LACRT-shRNA
Cat No 
shAAV-213630
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LACRT.

shAAV-213630
AAV-h-LACRT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LACRT (lacritin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
LACRT is highly expressed in the lacrimal glands and localized primarily to secretory granules and secretory fluid. It augments lacrimal acinar cell secretion, promotes ductal cell proliferation, and stimulates signaling through tyrosine phosphorylation and release of calcium.
Gene ID
90070
Gene Name (Vector)
lacritin
Gene Symbol
LACRT
HGNC ID
HGNC:16430
ORF Size (aa)
417
RefSeq ID
NM_033277
RefSeq Synonyms
NM_033277, BC069317, BC062217,
Species
human
UniGene ID
Hs.307096

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.