human KRT14 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KRT14.
shAAV-213376
AAV-h-KRT14-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KRT14 (keratin 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CK14;CK-14;cytokeratin 14;Cytokeratin-14;EBS3;EBS4;K14;keratin 14, type I;keratin, type I cytoskeletal 14;Keratin-14;NFJ
Description (eCommerce)
Cytokeratin 14, a member of the intermediate filament family of keratins, is a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. [taken from NCBI Entrez Gene (Gene ID: 3861)].
Description (Vector)
KRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. KRT14 product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Gene ID
3861
Gene Name (eCommerce)
keratin 14
Gene Name (Vector)
keratin 14
Gene Symbol
KRT14
HGNC ID
HGNC:6416
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
Protein Name (eCommerce)
Keratin, type I cytoskeletal 14
RefSeq ID
NM_000526
RefSeq Synonyms
NM_000526, BC094830, BC042437, BC019097, BC002690,
Research Areas
Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Cytokeratin 14, a member of the intermediate filament family of keratins, is a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. [taken from NCBI Entrez Gene (Gene ID: 3861)].
UniGene ID
Hs.654380
UniProt ID (eCommerce)
P02533
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.