human KNG1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KNG1.
shAAV-213334
AAV-h-KNG1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KNG1 (kininogen 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDK; BK; KNG
Description (Vector)
KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
3827
Gene Name (Vector)
kininogen 1
Gene Symbol
KNG1
HGNC ID
HGNC:6383
ORF Size (aa)
1284
ORF Size (bp)
1284 bp
RefSeq ID
NM_000893
RefSeq Synonyms
NM_001166451, NM_001102416, NM_000893, BC060039,
Species
human
UniGene ID
Hs.77741
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.