human KLK8 shRNA silencing AAV

Name
AAV-h-KLK8-shRNA

Cat No
shAAV-213304

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KLK8.

shAAV-213304

AAV-h-KLK8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK8 (kallikrein related peptidase 8). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HNP; NP; NRPN; PRSS19; TADG14

Description (Vector)

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.

Gene ID

11202

Gene Name (Vector)

kallikrein related peptidase 8

Gene Symbol

KLK8

HGNC ID

HGNC:6369

ORF Size (aa)

783

ORF Size (bp)

783 bp

RefSeq ID

NM_007196

RefSeq Synonyms

NM_144507, NM_144506, NM_144505, NM_007196, NM_001281431, BC040887,

Species

human

UniGene ID

Hs.104570

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.