human KLK4 shRNA silencing AAV

Name
AAV-h-KLK4-shRNA

Cat No
shAAV-213294

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KLK4.

shAAV-213294

AAV-h-KLK4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK4 (kallikrein related peptidase 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI2A1; ARM1; EMSP; EMSP1; kallikrein; KLK-L1; PRSS17; PSTS

Description (Vector)

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined.

Gene ID

9622

Gene Name (Vector)

kallikrein related peptidase 4

Gene Symbol

KLK4

HGNC ID

HGNC:6365

ORF Size (aa)

765

ORF Size (bp)

765 bp

RefSeq ID

NM_004917

RefSeq Synonyms

NM_004917, NM_001302961, BC096178, BC096177, BC096175, BC069489, BC069429, BC069403, BC069325,

Species

human

UniGene ID

Hs.218366

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.